Abstract

This study aims to investigate the effects of GlyNAC on planaria tissue regeneration and behavioral changes. There has been a focus on anti-aging in the older population due to the adverse effects that come with it such as muscle fatigue, a decrease in tissue regeneration, etc. As a result, there was an increase in research on finding an effective supplement to combat health issues and aging. GlyNAC, a combination of Glycine and N-acetylcysteine, has been shown to reverse and improve health by increasing glutathione levels. Glutathione is an antioxidant with multiple health benefits such as protecting against oxidative stress, a main factor in causing cell death. This experiment was conducted using planarians because they have a similar central nervous system, tissue regeneration, and glutathione production to humans. There were 1 control group and 3 experimental groups. The control group was fed regular ground beef while the experimental group was fed ground beef with GlyNAC. For tissue regeneration, each group would be measured and observed before and after the ground beef or GlyNAC-mixed ground beef. The planarians’ motility was recorded for 20 minutes with grid paper underneath their petri dishes. The results indicate that GlyNAC treated groups had increased regeneration and movement. With this support, our hypothesis of GlyNAC increases the regeneration and movement in planarians. Future Research can be done by having bigger experimental groups for more accurate data. Introduction GlyNAC There has been an interest in anti-aging in the modern day due to one’s fear of aging and the many symptoms that come with it, such as muscle fatigue, inflammation, a decrease in tissue

Abstract

Get ready to slide into the driver's seat of Drift Boss, a deceptively simple yet addictive driving game where timing is everything. Forget complex controls; this game is all about the one-button mechanic. Your mission is to navigate endless, winding tracks floating high in the sky, drifting around sharp corners with perfect precision. It sounds easy, but the procedurally generated paths demand intense focus and quick reflexes. As you collect coins and unlock unique vehicles—from taxis to fire trucks—you’ll find yourself hooked, constantly chasing that next high score. Can you stay on track, or will you plummet into the abyss?

Abstract

This experiment analyzed the effects of pomegranate juice on C. elegans under thermal stress.  C. elegans, a nematode with similar genes to humans, is an effective model for studying human diseases. Thermal stress occurs when an organism is exposed to high temperatures, which results in the release of heat shock proteins. Heat shock proteins act as molecular chaperones that help restore protein homeostasis following heat stress. Despite their presence, thermal stress can still weaken antioxidant defense in organisms. However, pomegranate juice is rich in antioxidants and polyphenols, which can help strengthen antioxidant defense. In this study, pomegranate extract was dissolved in water and mixed with agar powder. Using this pomegranate mixed agar, E. coli was cultured for 24 hours. The results showed that the 5 mg/ml concentration increased survival rates of C. elegans. However, the 10 and 20 mg/ml concentrations lowered survival rates, which can be attributed to dose-dependent toxicity. Interestingly, the higher concentrations of pomegranate extract significantly increased C. elegans reproductive rates. This research expands on previous studies that examined the effect of pomegranate juice on C. elegans and distinctly focuses on its role under thermal stress. This distinction helps gain a deeper insight into pomegranate juice's effect on oxidative stress.